Selected primary antibody| GSK3β Mouse Monoclonal antibody recommendation

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Glycogen synthase kinase-3 (GSK-3) is a
serine-threonine kinase that has been evolutionarily very conservative.The
protein encoded by GSK3β (glycogen synthase kinase 3 beta) is a
serine-threonine kinase, belonging to the glycogen synthase kinase subfamily.
It is involved in energy metabolism, neuronal cell development, and body
pattern formation.

GSK-3β can also act on many signaling
protein structural proteins and transcription factors, and regulate cell
differentiation, proliferation, survival and apoptosis. GSK-3β is a key enzyme
involved in liver glucose metabolism. It inhibits its activity by
phosphorylating GS, reduces liver glucose synthesis, increases blood glucose
concentration in the body, is controlled by insulin in the insulin signaling
pathway, and participates in liver glucose metabolism.

Polymorphisms in GSK3β have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of GSK3β may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for GSK3β .

The picture is from https://link.springer.com/article/10.1007/s12035-013-8571-y

AbbkineGSK3β Mouse Monoclonal antibody (1A6) helps basic research! Basic information about the product:

Product name	#CAT	Reactivity	Applications	Dilution ratio	Observed Band(KD)
GSK3β Mouse Monoclonal antibody (1A6)	ABM0076	human/mouse/rat	WB/IHC-P	WB (1:1000-1:2000) IHC-P (1:100-1:200)	46 kD

GSK3β Mouse Monoclonal antibody (1A6)
verification results:

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using GSK3β Mouse mAb diluted at 1:200.

Immunohistochemical analysis of paraffin-embedded Human Stomach Carcinoma Tissue using GSK3β Mouse mAb diluted at 1:200.

Western blot analysis of 1) Hela Cell Lysate, 2) 3T3 Cell Lysate, 3) Rat Brain Tissue Lysate using GSK3β Mouse mAb diluted at 1:1000.