It's time to release new products every month, so it's exciting to think about it! After the hard work of our R & D personnel, Abbkine welcomed 7 new partners in May! The new product line of this issue-glutathione series biochemical kits.
The significance of glutathione research:
Glutathione is a
tripeptide containing glutamate, cysteine and glycine, which contains
sulfhydryl groups. It is widely present in animals and plants. It has
antioxidant and integrated detoxification effects. Its related coenzyme is
NADPH.
Too much free
radicals produced by the body's metabolism can damage the biofilm, invade
macromolecules of life, accelerate the body's aging, and induce the production
of tumors or atherosclerosis. Glutathione has the functions of enhancing the
antioxidant function of organisms, promoting growth, and enhancing the
influence of organisms on the adverse environment in the human body. Its main
physiological role is to remove free radicals in the body. It is also a good
antidote, which can weaken the toxicity of toxic substances and remove toxic
substances from the body. Glutathione also promotes growth and improves human
immunity.
Glutathione can
be used not only as a medicine but also as a base material for functional
foods, and is widely used in functional foods such as anti-aging, enhancing
immunity and anti-tumor.
Interpretation of
new products：
1) CheKineTM Reduced Glutathione (GSH) Colorimetric Assay Kit: Application notes DTNB reacts with reduced glutathione to form a yellow product. The optical density measured at 412 nm, can directly reflect glutathione concentration in the sample.
2) CheKineTM
Glutathione Oxidized (GSSG) Colorimetric Assay Kit: Reduced glutathione can
react with DTNB and generate 2-nitro-5-mercaptobenzoic acid, which has the
maximum light absorption at 412nm wavelength.
3) CheKineTM
Glutathione Reductases (GR) Colorimetric Assay Kit: GR can catalyze the reduction
of NADPH to GSSG to regenerate GSH, and NADPH dehydrogenates to produce NADP +;
NADPH has a characteristic absorption peak at 340 nm, while NADP + has no
absorption peak at this wavelength; NADPH dehydrogenation rate is determined by
measuring the decrease rate of absorbance at 340 nm to calculate GR activity.
4) CheKineTM
Glutathione S-Transferase (GST) Colorimetric Assay Kit: GST catalyzes the
binding of GSH to CDNB. The conjugation is accompanied by an increase in
absorbance at 340 nm. The rate of increase is directly proportional to the GST
activity in the sample.
5) CheKineTM
Glutathione Peroxidase (GSH-Px) Colorimetric Assay Kit: GSH-Px catalyzes H2O2
to oxidize GSH to produce GSSG; glutathione reductase (GR) catalyzes NADPH to
reduce GSSG to regenerate GSH, while NADPH oxidizes to produce NADP+; NADPH has
a characteristic absorption peak at 340 nm, while NADP+ does not; NADPH
dehydrogenation rate is determined by measuring the decrease rate of absorbance
at 340 nm to calculate GSH-Px activity.
6) CheKineTM
Thioredoxin Reductase (TrxR) Colorimetric Assay Kit: TrxR can catalyzes the
reduction of DTNB by NADPH to generate TNB and NADP+. TNB has a characteristic
absorption peak at 412 nm. TrxR activity can be calculated by measuring the
increase rate of TNB at 412 nm.
7) CheKineTM
Thioredoxin Peroxidase (TPX) Colorimetric Assay Kit: TPX catalyzes H2O2
to oxidize dithiothreitol (DTT). The absorption wavelength of H2O2
is 240nm. TPX activity can be calculated by measuring the decrease rate of
absorbance at 240nm and subtracting H2O2 catalyzed by
catalase (CAT). Therefore, this kit can measure TPX and CAT activities of
samples simultaneously.
New product list:
CAT# | Product name | classification |
KTB1600 | CheKine™ Reduced Glutathione (GSH) Colorimetric Assay Kit | Cell metabolism |
KTB1610 | CheKine™ Glutathione Oxidized (GSSG) Colorimetric Assay Kit | Cell metabolism |
KTB1620 | CheKine™ Glutathione Reductases (GR) Colorimetric Assay Kit | Cell metabolism |
KTB1630 | CheKine™ Glutathione S-Transferase (GST) Colorimetric Assay Kit | Cell metabolism |
KTB1640 | CheKine™ Glutathione Peroxidase (GSH-Px) Colorimetric Assay Kit | Cell metabolism |
KTB1650 | CheKine™ Thioredoxin Reductase (TrxR) Colorimetric Assay Kit | Cell metabolism |
KTB1660 | CheKine™ Thioredoxin Peroxidase (TPX) Colorimetric Assay Kit | Cell metabolism |
Abbkine focuses on the fields of immunology and cytology, and is committed to innovating and developing various types of antibodies, proteins, analytical reagents and kits, with a view to becoming a key promoter in the fields of life science research and development, and drug development. Here, we present to you the favorite products of protein and immune research users, from basic immunological products, such as protein extraction and quantification, to internal reference label antibodies, primary and secondary antibodies for immunological experiments; cell research users’ favorite Products ranging from dyes and kits for cell state detection, organelle extraction kits, cell substructure staining and cell metabolism detection products, to cytokine and protein detection kits for cell culture, just to help you Research career!
About Abbkine
Scientific Co., Ltd.
Abbkine
Scientific Co., Ltd. was founded in 2012. Our mission is to become a respected
and world-class supplier of biomedical products and services. Through a clear
core strategy and a corporate culture that promotes learning, innovation,
cooperation, and excellence, we will stimulate our inherent creativity, provide
competitive biomedical products and services, and continue to create maximum
value for customers and achieve our mission.
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