ABCB5 Monoclonal Antibody Review

ATP-binding cassette sub-family B member 5 also known as P-glycoprotein ABCB5 is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells.

Abbkine ABCB5 Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody was validated for WB, IF, IHC-p and tested to react with Human. Abbkine suggested the starting dilutions are as follows: WB: 1:2000, IF: 1:200, IHC-p: 1:200. Optimal working dilutions should be determined by users.

After several times failure of using other brands of ABCB5 Antibody, I found Abbkine through internet. What I have to say: the antibody is amazing. It saves my experiment and my time. I applied the antibody in WB, IF, IHC. All the results are in line with my expectations. Compared with other brands, the price of this antibody is even lower. There is no doubt that I’ll purchase products from Abbkine again.